We study how translational control shapes immune cell function and how defects in protein synthesis cause human disease.
Emmy Noether Group Leader
Molecular biologist studying mRNA translation, human genetics, and molecular immunology at the Gene Center Munich.
Our work spans three interconnected areas of translational control in immunity.
How do T cells rewire their translational machinery during activation, differentiation, and effector function?
Understanding how monogenic ribosome defects lead to selective immunodeficiency syndromes.
Investigating the links between tRNA biogenesis, modification, and autoinflammatory disease.
Latest news from the lab, including publications, grants, and milestones.
Demonstrates that somatic CBL deficiency selectively impairs B cell development while sparing T cell function, revealing cell-type specific requirements for this E3 ubiquitin ligase.
Collaborative work on YEATS4 variants and resistance to tuberculosis now published.
Awarded the prestigious Emmy Noether grant from the DFG to establish an independent research group.
Received Erstförderung from Fritz Thyssen Stiftung to support our research programme.
New studies in Science Immunology (LY9 and CD4+ T cell immunity) and Molecular Therapy (CBL TKBD conformation).
We're always looking for curious and motivated scientists to join our team at the Gene Center Munich.
See Open PositionsThe Bohlen Lab is located at the Gene Center of Ludwig-Maximilians-Universität München, one of Europe's leading research universities.
Get in touch
Our research is supported by the Emmy Noether Programme of the German Research Foundation (DFG).
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